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SAM / BAM / CRAM (Sequence Alignment Map)

Exchange Schema Genomics openly published

Samtools organisation for next-generation sequencing developers: htslib C API, htsjdk Java API, file format specifications, and samtools/bcftools source code.

GA4GH / hts-specs, from their own meta description

Other genomics data models

GFF3 / GTF Exchange Schema HGVS nomenclature (Human Genome Variation Society) Code System VCF (Variant Call Format) Exchange Schema
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Model Details
Steward GA4GH / hts-specs
Origin International
Layer Exchange Schema
Domain Genomics
Status live
Access Openly published
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How I know this

Compiled for the API Evangelist data model catalog, then confirmed against the steward's own site.

Confirmed 2026-08-11

Evidence: name evidence 3/3. Found something wrong? Tell me — corrections are cheap and I would rather be right.

Modernity Profile
Access Open
Assessed 43.0% of the rubric

Not enough of this standard was readable to place it in a band. That is a limit of what I could see, not a finding against the standard.

A separate measure from the Kin Score, which rates API providers. This rates how current a standard is in how it is expressed, published and paid for — not how good it is. EDIFACT and X12 score low here and move an enormous share of world trade.

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